Esomeprazole EC + Itopride SR Pellets
Rraynex supplies Esomeprazole EC + Itopride SR Pellets as enteric-coated / sustained-release pellets in the PPI + Prokinetic category, in a strength of 40 mg + 150 mg.
Product overview
Esomeprazole, the S-isomer of omeprazole, is a proton pump inhibitor used for GERD, erosive oesophagitis and prevention of NSAID-associated ulcers.
Itopride is a prokinetic agent used for functional dyspepsia and in combination with PPIs.
Pharmaceutical pellets are small, free-flowing spherical units filled into capsules or compressed into MUPS tablets. Dividing a dose across many pellets gives more reproducible gastric transit and release than a single-unit tablet.
Formulation and release profile
Enteric-coated (EC) pellets carry a polymer coat that stays intact in the acidic stomach and dissolves at the higher pH of the small intestine, protecting acid-sensitive drugs and delaying release.
Sustained-release (SR) pellets release the drug gradually through a release-controlling coat or matrix, flattening plasma peaks and reducing dosing frequency.
Combination pellets deliver two actives in one multiparticulate product, usually with each active in its own pellet population and release profile, for fixed-dose capsule formulations.
Pharmaceutical applications
- Capsule filling of esomeprazole ec + itopride sr pellets for acid-suppression products.
- Multiparticulate dosage forms where reproducible release matters.
- Formulation development, scale-up and commercial supply programmes.
Product specifications
- Product
- Esomeprazole EC + Itopride SR Pellets
- Form
- enteric-coated, sustained-release Pellets
- Therapeutic category
- PPI + Prokinetic
- Strength
- 40 mg + 150 mg
- Grade
- IP / BP / USP / EP
- Pack size
- 25/50 kg
- Site certifications
- WHO-GMP, ISO 9001, ISO 14001
Detailed specifications, COA and technical documentation are shared on request.
Supply and enquiries
Rraynex supplies Esomeprazole EC + Itopride SR Pellets to pharmaceutical manufacturers, formulation developers and CDMOs in 25/50 kg packs with batch traceability. Send your quantity, grade and documentation needs through the enquiry form and the commercial team will reply with specifications and a quotation. Rraynex is a B2B supplier and does not sell to consumers.
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